Diagnosis of beta thalassemia

Diagnosis of beta thalassemia

The diagnosis consists of a test of blood strength (hemoglobin) and electrolysis of blood components

In all types of disease, anemia similar to that found in iron deficiency anemia appears to be associated with decreased red blood cells (MCV, MCH, MCHC).

• Small : 1 – concentration of hemoglobin 10-12 g / dl

2 – increase in the proportion of hemoglobin A2 in electrolysis

• Middle finger : 1 – concentration of hemoglobin 8-10 g / dl

2 – a slight increase in the proportion of hemoglobin A2 and hemoglobin F with the presence of hemoglobin A in electrolysis

• Great : 1 – concentration of hemoglobin less than 8 g / dl

2. Significant increase in the proportion of hemoglobin F and increase in hemoglobin A2 with no hemoglobin A in electrolysis of blood.

The action of a film or picture of blood shows the following:

1. Red blood cells of the type (Microcytic Hypochromic)

2 – irregular size of red blood cells (Anisocytosis)

3 – the existence of red blood cells in different forms, most notably the pellets targeted (Schistocyte) Target pellets (Target cells)

Red blood cell decomposition leads to an increase in Reticlocyte and increased bilirubin.

Due to the expansion of the bone marrow distances in the skull, the radiance of the skull appears in the form of cut hair.


1. Oxford handbook of clinical medicine 8th edition

2. Dvidson’s principles and practice of medicine 21st edition

3. illustrated texte of pediatrics -Tom lissauer, Graham Clayden 3rdedition