Rickets are known to be a disease in children due to a defect in the deposition of bone minerals such as calcium and phosphorus during the growth stage, leading to bone thinness and fragility.
General causes of rickets
- Do not expose the pregnant mother to the sun during her pregnancy because of covering her face.
- Lack of calcium and vitamin D deficiency in food. One of the most important dietary sources of vitamin D is milk and dairy products such as milk, cheese, butter, cream, eggs, fish oil and liver.
- The incidence of rickets in children of prematurity increases
- The incidence of rickets in people with kidney disease and liver disease
- The incidence of rickets increases when taking drugs such as cadmium, lithium, iron, fluoride, aluminum, and some anticonvulsants.
Genetic causes of rickets
- Deficiency of alpha-hydroxylase enzyme, or hydroxylase deficiency, leading to so-called vitamin D-based rickets (type I)
- Resistance of vitamin D receptors to vitamin D effects leading to vitamin D-dependent rickets (type II)
- Lack of calcium and increased secretion of thyroid glands as well as lack of secretion
- Infection of the genetic phosphate deficiency associated with chromosome X or body chromosomes
- DENT, FENCON and LOW (which affect the brain, kidney and eye at the same time)