Gout can show signs and conditions according to the condition in which there is acute and chronic condition and also form the contract and effect on the kidneys. The acute gout infection is usually in one joint. The primary complaint is pain in more than 90% of the patients. It affects the small joints in the limbs, especially the lower limb and specifically the joint between the instep and the metatarsal-phalangeal joint. Symptoms and signs of the disease in 50% of the infected. It is important to note that the acute seizure begins abruptly and peaks within 10 hours and the joint is reddened. This redness of the joint may resemble a contagious infection. Skin flaking may occur after the nubia is removed, and the temperature is warm and is clearly painful when touched or pressed. Arthritis is followed by inflammation of the joint capsule, which reduces the movement of the joint, and ends automatically within 5-14 days. The remaining 10% of patients have polyarticular arthritis, especially in older women who take diuretics. These patients have a high temperature and appear to have a toppi contract without prior severe seizures.
The symptoms change in the absence of treatment, where the symptoms become more than one joint. Although more than one joint is included, the inflammation is less severe. It also includes near-trunk and upper-extremity joints and seizures are more frequent , And last longer. Gout can cause inflammation of the membranes outside the joint, such as covering the muscles.
Tophi is a collection of crystals of uric acid salts in soft tissue, which occurs in half of the patients in untreated gout, usually on the outer edge of the ear and in other places such as fingers and toes. It should be noted that the contract arises after 10 years of the first bout of gout in people who have not received treatment and have suffered from chronic gout.
As mentioned above, acute seizures (flare up) when drinking alcohol, eating a large amount of food containing purines, bruising, bleeding or dryness, or using a drug increases the level of uric acid, The seizures may also occur when uric acid deficiency is the same as in the use of radiocontrast dye or low-dose uric acid such as allopurinol,