It is intended to reduce symptoms and signs and reduce the proportion of uric acid through some drugs described by the doctor when the diagnosis of the disease, in the case of acute gout is given painkillers and anti-inflammatory (Nsidz) and preferably used when there are no health problems such as inflammation or ulcers in the stomach or kidney failure As mentioned above, the use of aspirin in small doses leads to an increase in uric acid in the blood, so start with large doses of aspirin.
As well as the use of steroid compounds by oral or intravenous or intramuscular injection or direct injection within the joint, and uses colchicine, an anti-inflammatory, which is used during the first 24 hours of acute attack to be effective enough and the important side effects of the drug vomiting and diarrhea, which occurs in 80 % Of patients.
As for the treatment of chronic gout, the aim is to reduce the level of uric acid to 6 mg / deciliter or less, and this is followed by a particular diet in addition to drugs that reduce uric acid in the blood, and the use of these drugs should be signs of frequent episodes of acute gout or The presence of a contract or signs of damage to the joint or bone, the association of disease with kidney disease or the presence of the disease with a significantly higher level of uric acid more than 9 mg / dL.
The drugs used are propanide, which increases uric acid output through the kidneys in the urine and has few side effects and people who consume it need to drink large amounts of fluids to reduce damage to the kidneys, either kidney stones or kidney disease.
Alopurinol reduces the formation of uric acid by inhibiting the work of the enzyme Xanthine (oxidase), which is used in cases where the cause of the increase in the increase in the manufacturing and also during the chemotherapy of tumors, and the most important side effects have dyspepsia, headache, diarrhea and skin rash, and In rare cases, patients may experience hypersensitivity caused by the use of alopurinol, which is dangerous, where the rate of survival is 20-30%, which is most likely to those who have impaired kidney function.
It should be noted that precautions should be taken when using drugs that reduce uric acid because the low level of acid in the blood quickly lead to a severe bout of gout.