Treatment of vitiligo with medicine and radiation

Treatment of vitiligo with medicine and radiation

Exposure to many tragic social events such as exposure to traffic accidents and disabilities and problems that cause sudden death of loved ones all affect the infection of vitiligo

Using sunscreens: This is done in order to protect the affected area from sunburn and reduce the color of the healthy area. The sun visor, which contains more than 30 sun protection factor, is ideal for these targets.

Repigmentation: It is a permanent re-pigmentation of melanin and this is achieved for small spots (identified) by topical cortisone creams and Sorrelin creams with exposure to ultraviolet radiation, but for widespread vitiligo is used suralin but orally by exposure to ultraviolet A.

1- Corticolor creams: The treatment starts intermittently with four weeks of treatment and two weeks without treatment. It is effective for vitiligo. If there is no response within two months, it is considered ineffective because of the differences in response.

2- Calcinurine-inhibiting creams: Tacrolims are effective in treating sun-exposed areas and are more effective in the use of ultraviolet radiation.

3- Soralin cream with ultraviolet radiation A: It is used by an experienced specialist and in cases with small patches.

Oral Surrogates with Ultraviolet A (PUVA): Suralin should be taken as oral pills and after 2 hours, the patient should be exposed to UV rays. PUVA should continue to be exposed 2-3 times a week. It is useful for treating vitiligo and its high efficacy (85%) in more than 70% With vitiligo spread in the neck, head, upper limbs and trunk. It needs at least a year to show the desired results.

Exposure to ultraviolet B narrow beam: The patient is exposed to radiation B for a number of seconds at the start of the treatment session and then gradually increase as determined by the doctor in charge of the situation. It is not necessary to take pills as in the case of radiotherapy A, and the treatment sessions (three sessions per week) and improve after 15 – 20 sessions on average, and is the best treatment for children under the age of 6 years.

6 – laser treatment by means of the enzyme: It is used to treat vitiligo in the face.

7 – the use of creams similar to vitamin D: In order to help the success of radiation therapy.

• Depigmentation therapy: It is used to give the skin one color and is used when vitiligo is widespread or when failure or rejection of radiation therapy.

The removal is done by using monobenzylether cream of 20% (MEH) hydroquinone and this removal is permanent and not reversible. The success rate is greater than 90% and the last color after removal is the color of chalk, which is the color of the areas affected by vitiligo.

After removing the color, the patient must use sunscreen for life and avoid exposure to excess sunlight because of the increased chance of sunburn after removal.

1. Vitiligo is an acquired chromosome caused by the breakdown of the responsible colored cells. It is the production of the melanin dye that is responsible for giving the skin color

2 – The mechanism of the crash of colored cells is the crash by self-immunity or breakage due to toxic substances resulting from the manufacture of melanin or the result of stress oxidation

3. Vitiligo spreads around the world and the incidence rate is 1%. There is no difference between males and females in the infection, and most cases occur in people between the ages of 10 to 30 years.

Vitiligo is divided into two types: general vitiligo, which is the most common, and there is a satisfactory biography in the family in addition to the existence of autoimmune diseases (diseases of the thyroid, diabetes, and Edison) and vitiligo is the least common and is not linked to the existence of a satisfactory biography in the family or the existence of immune diseases Self.

5 – The most vulnerable areas are exposed areas of the sun are hands, feet, arms, neck and face, especially around the mouth and eye.

6 – Vitiligo appears in the form of white patches similar to the color of chalk and be specific features, and may appear Vitiligo tricolor.

7 – The diagnosis depends on the clinical examination and examination of the affected area of ​​the wood lamp, in addition to ascertaining the symptoms and signs of autoimmune diseases and ask for tests if necessary in case of doubt.

8. Medications include the use of sunscreens, topical cortisone creams, cream and sorrelin pills

9. Radiation therapy includes the use of ultraviolet A and ultraviolet B, narrow beam and laser.

10. Surgery involves the use of suction or vaccination.

11 – Pill of honey, honey, ammonia, garlic, vinegar, milk and narcissus are used in alternative medicine to treat vitiligo

1. fitzpatrick’s color atlas and synopsis of clinical dermatology 6th edition

2. Dermatology, Fourth Edition By Richard P.J.B. Weller, John A.A. Hunter, John A. Savin and Mark V.Dahl