ANA analysis and body immunity
The immune system is concerned with the process of defending the body, through the lines of defense that it forms in front of the pathogens. Each defense line has a certain defense mechanism that differs in style and defensive force. The front lines usually have a comprehensive purifying effect towards the pathogens of the body. The immune system begins with the principle of specialized defense of the body. The process becomes complex for the front lines. The type of elements that attack the body and the building of antibodies within it are studied within a specific program that allows the immune system to However, certain immune system disorders may occur in terms of the identification of the attacking objects, and the enemy of the body, attacking certain cells of the body, thought to be objects Hostile, by building antibodies to it.
The severity of the attack of the immune system of the body is different, which requires a study to measure the severity of these defensive strikes directed to determine the extent of damage to the body, and then required to disclose the extent of the attack of the immune system, which is called autoimmune diseases, which vary in strength, The body of disease to another, so it was the best means of detection is the work of analysis shows the amount of antibodies produced by the body’s immune system, against the nuclei of cells, which is called ANA analysis.
ANA analysis method
A sample of the blood of the patient to be analyzed and then placed on a microscope slide of an ultrasound microscope, so that the test slice contains cells equipped for this purpose, to interact with the antibodies to the nuclei of the cells, if any, and thus appear under the microscope after The ultraviolet light is light and bright, within the sample of the examination, which gives a positive result of the examination, by the presence of an indicator of autoimmune disease, which was determined by determining the presence of these antibodies throughout the analysis.
It should be noted that some people have a positive test without any autoimmune disease, they may be up to 5% of the test samples, this analysis does not mean the concentration of the need for the existence of a specific disease in itself, but only indicates the possibility of disease , Which prompts the doctor to search for it correctly, according to the following ratios:
- The sensitivity of the test positive is up to 30%, indicating rheumatoid arthritis, tuberculosis, chigren’s disease, HIV / AIDS, or endocarditis.
- Sensitivity rate of up to 65%, indicating the presence of liver diseases, or some diseases of the crucifixion, such as scleroderma.
- Sensitivity of up to 94% refers to the presence of lupus erythematosus, or pharmacokinetics caused by certain types of drugs, such as penicillamide, hydrolyzine, brocyanamide, etc.