Copper cycle and Wilson’s disease

Copper cycle and Wilson’s disease

Copper cycle in the body and histological examination of the disease

Copper in the food is absorbed into the stomach and upper intestine, and then transmitted to the liver by blood linked to albumin. In the liver, copper is linked to the core of seriroloplasmine leading to the formation of serioloplasmamine. Serioloplasmine is a glycoprotein made in the liver and excreted in the blood, Copper is excreted by bile extract

However, when examining the tissue of the liver, it is noticed that the changes in the tissue range from chronic inflammation to cirrhosis characterized by its large grains. The blood portal system is also seen. The area of ​​the base contract in the brain is destroyed, and the renal tubes are destroyed. There are also certain small areas of destruction in the bone.