Liver fibrosis
Liver Fibrosis occurs when the liver tries extensively to repair damage and scars that occur as a result of chronic damage. Conductive tissue accumulates due to excess extracellular matrix production, slow decomposition, It is worth mentioning that cirrhosis affects the form and function of the liver tissue. However, there are no symptoms on the patient unless the fibrosis develops into advanced conditions such as cyanosis and others.
Medical treatments for liver cirrhosis
The treatment of cirrhosis depends on the method of development of the disease, and the treatment aims at three basic goals, as follows:
Find out why and treat it
Knowing the cause and treatment may contribute to prevent the development of cirrhosis of the liver, and may lead to the decline of fibrosis and the return of the liver to normal in some cases, and causes leading to cirrhosis of the liver include:
- Diseases of the alcoholic liver: In cases where fibrosis is caused by alcoholic liver disease, alcohol must be avoided to treat the problem.
- Bile duct obstruction: If fibrosis is caused by biliary obstruction, these blockages should be removed.
- Hemorrhagic deposition Heavy metals should be disposed of as iron when fibrosis is caused by hemochromatosis.
- Wilson’s disease: Wilson disease is a rare genetic disease. It causes copper to accumulate in important organs such as the liver and brain. Treatment of the disease and the elimination of accumulated copper may lead to cirrhosis.
- Hepatitis B: Hepatitis B cirrhosis is treated by elimination of the virus. Hepatitis B is treated with antiviral drugs such as Entecavir ), Tenofovir, lamivudine, adefovir, and Telbivudine. In some chronic cases, interferon alfa injections may also be used.
- Hepatitis C: The virus that causes chronic hepatitis C is eliminated for controlling the resulting fibrosis, which can be treated with modern hepatitis C antiviral drugs. These medications are given as the doctor deems appropriate. With other drugs, including Simeprevir, Daclatasvir, Sofosbuvir, Ledipasvir, Velpatasvir, Ombitasvir, Baritabrivir, (Paritaprevir), and Rituna Ritonavir, and Dasabuvir.
Knowledge of common conditions
Comorbidity must be studied and taken into consideration in the treatment of cirrhosis. Control can reduce cirrhosis of the liver. Metabolic syndrome is defined as the combination of factors In the same patient: elevated blood pressure, high blood sugar, increased waist fat, and abnormal readings of triglycerides or triglycerides.
Treatment of fibrosis itself
In cases where the cause of the cause is not successful or the cause can not be treated, remedial measures should be taken that may reduce fiber synthesis or stimulate the breakdown of fibrolysis.
Botanical cirrhosis treatments
Although there are many herbal remedies that are thought to be able to control cirrhosis, effective therapeutic options are very limited because of the diversity of the mechanism of disease progression. Here are some herbal remedies that contribute to controlling cirrhosis:
Herbs with antiviral effect
There are some herbs that extract some antiviral substances that weaken chronic hepatitis including hepatitis B and hepatitis C, such as Scutellaria baicalensis and Japan’s Sophora japonica, Rhodiola kirilowii, Glycyrrhiza glabra and Citrus unshiu.
Herbs with anti-inflammatory effect
Herbs containing anti-inflammatory substances include Salvia miltiorrhiza, Betula platyphylla var. Japonica, and other Chinese herbs.
Antioxidant herbs
Of plants whose extracts have anti-oxidant effects, the herbaceous plant (Silybum marianum) and the acanthus ilicifolius, which also have an anti-inflammatory effect, as well as turmeric ), And others.
Diagnosis of cirrhosis
Cirrhosis is diagnosed by clinical examination in cases where it is expected to occur as chronic liver disease cases, such as hepatitis C, hepatitis B, alcoholic liver disease, or abnormal liver function tests (in English: Liver Function Tests, and by performing the appropriate tests, the presence of fibrosis or the presence of fibrosis, in addition to the ability to determine the severity of fibrosis, if any, to take the proper medical procedures in treatment, and these tests include:
- Non-invasive imaging tests: Noninvasive Imaging Tests can detect evidence of cirrhosis and portal hyperpertension, such as splenomegaly and Varices. ), But its sensitivity in detecting cases of intermediate and advanced fibrosis decreases when there is no enlargement of spleen or varicose veins. These imaging tests include ultrasonography, computerized tomography, and magnetic resonance imaging YZE: Magnetic Resonance Imaging.
- Take a biopsy of the liver: Liver biopsy is the main criterion for cirrhosis diagnosis, its degree and causes, but it can not always be performed because it requires surgery within the body. The patient may feel pain after taking the biopsy, Take it or analyze it.
- Blood tests: Blood tests are performed to give the results of direct and indirect laboratory markers such as Serum Bilirubin, the ability to determine whether the fibrosis does not exist, or is present more or less severe than the simple , But can not differentiate between cases of fibrosis medium and severe, and then can be used to take a biopsy of the liver after a blood test that confirmed the presence of fibrosis.