Diagnosis of Addison’s disease

Diagnosis of Addison’s disease

Diagnosis of Addison’s disease

The presence of symptoms and signs and the suspicion of the existence of this disease requires a test called short synacten test (a short synacthen test), which is a hormone regulator of the adrenal gland is a plant that stimulates the secretion of cortisone.

A blood sample is taken before the hormone is given. It is given to measure the proportion of cortisone in the blood. 550 nm / liter

Therefore, the lower response of the natural confirms the lack of function of the adrenal gland or whether this deficiency is due to the adrenal gland itself (Edison) or that this deficiency is the pituitary (pituitary adrenal insufficiency) and to distinguish between them there are three differences, the first is the presence of pigments In Adison’s disease and its absence from the pituitary adrenal insufficiency. The second is the examination of the hormone regulating the adrenal gland, which is high in the disease of Edison and low in the pituitary adrenal insufficiency, the third is the long test synaptin test (long synucthen test), giving Syanktin for five days and then The cortis is measured In the case of pituitary deficiency, cortisone increases because the main cause of the imbalance is the lack of the hormone regulating the adrenal glands and the gland is intact. One dose, as in the short test, does not alert the gland, while the long examination is alerted. In the case of Edison’s disease, the problem here is the damage of the gland itself. Respond to the hormone so cortisone concentration does not rise.

In order to determine the effect of the lack of mineral crustaceans or aldosterone, we must check the level of renin and dystrone in the blood. In the case of deficiency, aldosterone is low with high renin in the blood, and it is important to examine the salts of blood, especially sodium and potassium, there is a lack of sodium due to loss of urine And increase in potassium as a result of a few in the extraction by kidneys, and because of the increase in potassium must be done a heart plan to make sure of the actual increase of potassium and note changes to the planning.

Also, the sugar level test shows a decrease in this level and increase the acidity of the blood (acidosis) because of the reduction of the removal of hydrogen ions in the urine and thus decrease the pH (pH)
Other immunological diseases should also be examined if there is any doubt regarding the pathology and clinical examination. Radiology has an important role in the disease of Edison Fascist X chest may be useful in the presence of tuberculosis or tuberculosis, in addition to the examination of sensitivity to the skin and laboratory examination of phlegm, and the pictures of the layer of the abdomen may be useful, may show inflation in both cities in the case of tuberculosis or tumors or the disease of meat or may appear calcification in The glands, especially in tuberculosis, may appear in the immune system.