Treatment of Addison’s Disease

Treatment of Addison’s Disease

Drug therapy

Patients with adrenal insufficiency should have full knowledge of the disease and its complications and the need for lifelong treatment, taking into account the side effects of this treatment. Hydrocortisone (oral hydrocortisone 20 mg / ml and 10 mg / day to compensate for glycoproteins is an alternative to hydrocortisone, Pridnisolone is used 5 mg am and 2.5 pm Fludrocortisone is used and 50-100 micrograms are used each day to compensate for mineral crustaceans and to maintain the concentration of salts in the blood.

In the case of stress or disease, we must increase daily dose of hydrocortisone to 75-100 mg or prednisone to 20-30 mg / day. If the patient undergoes a major operation, the patient should be given 100 mg of intravenous hydrocortisone every 8 hours, and the next day, 50 mg intravenously every 8 hours and continue until he can eat and continue on the usual dose of 20 mg. Mg in the morning and 10 mg in the evening.

As for the treatment of the Ndosa is to give the solution of salt (NaCl) and glucose and give hydrocortisone intravenously, it is worth mentioning that if treated this case, they lead to death.

Before giving the usual dose, the doctor should confirm that the patient is free of tuberculosis or tuberculosis, diabetes, osteoporosis, gastric ulcers, evidence of high blood pressure or heart failure, and the presence or absence of psychiatric illnesses.

The side effects to be observed as a result of life-long steroid compensation are high blood pressure, high blood pressure, high blood sugar, obesity, muscle weakness and atrophy, edema, stomach ulcers, acne, And osteoporosis, and exposure to multiple infections due to the fact that steroid is an inhibitor of immunity, the emergence of hair in the body profusely.

To reduce these effects, it is advisable for the patient first to control the calories in the meals he ate in order to reduce the high level of sugar and to reduce obesity, and secondly reduce the salt and sodium to prevent the emergence of edema and reduce the high blood pressure, Treatment of acidity of the stomach and ulcers include antacids, inhibitors of H2 antagonist and proton pump inhibitors, and IV use of calcium and vitamin D derivatives to prevent osteoporosis.