The natural cell contains 46 chromosomes, where chromosomes are intertwined with each other. The body cell eventually contains 23 pairs of chromosomes. In Down syndrome, there are 3 chromosomes on pair 21 instead of chromosomes. Down syndrome produces 95% of the chromosomes. Due to the lack of division in the equal division of the egg or sperm and thus the total chromosomes is 47 chromosomes, and in 4% of Down syndrome results in the disease of the transition, where the chromosome moves from a certain pair to the husband number 21
Thus, the total number of chromosomes in the cell is 46 chromosomes, and in 1% of the children they have the cause of Down’s disease is the discoloration where some cells contain natural chromosomes in pair 21 thus total chromosomes are 46 chromosomes, and some cells contain 3 chromosomes Pair number 21 thus the total number is 47 chromosomes, and the differentiation occurs due to unfair inequitable divisions during the fetal development stage.